Dr. Dennis is the managing director of the Computing Technologies Research Lab (CTRL) at the David Geffen School of Medicine at UCLA, where he also received his PhD. His research interests and current projects focus on clinical and research data collection, Internet-based decision support authoring tools, interactive educational technology, database design and development to support online research systems and community web applications. Dr. Dennis is also the creator of the Mind-Matrix knowledge mapping system.

Currently, Dr. Dennis and his group work closely with CORE staff to provide programming and technical support to various projects, including Automated Evaluation of GastroIntestinal Symptoms (AEGIS), and OPERA.