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Brennan M.R. Spiegel
Eric Esrailian
Fasiha Kanwal
Gil Melmed
Lin Chang
Martijn van Oijen
Matthew Solomon
Roger Bolus

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Lin Chang, MD

Publications (24)
Lin Chang

Lin Chang is an Associate Professor of Medicine in the Division of Digestive Diseases and Department of Medicine at the David Geffen School of Medicine at UCLA.

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Publications by Lin Chang

Title Global outcome measure of Adequate Relief detects clinically meaningful improvement in pain and performs consistently across pain severity levels in Irritable Bowel Syndrome. 
Author(s) Ameen VZ, Health AT, Spiegel BMR, McSorley D, Chang L 
Publication Manuscript in primary submission 
Article PDF Not Available
Title Is irritable bowel syndrome a diagnosis of exclusion?: a survey of primary care providers, gastroenterologists, and IBS experts.  
Author(s) Spiegel BM, Farid M, Esrailian E, Talley J, Chang L. 
Publication American Journal of Gasteroenterology. 2010 105(4): 848-58. 
Article View/Download Article
Title Meta-analysis: do irritable bowel syndrome symptoms vary between men and women? 
Author(s) Adeyemo MA, Spiegel BM, Chang L. 
Publication Ailmentary Pharmacology & Therapeutics. 2010 doi: 10.1111/j.1365-2036.2010.04409.x. [Epub ahead of print] 
Article View/Download Article
Title Developing valid and reliable health utilities in irritable bowel syndrome: results from the IBS PROOF cohort. 
Author(s) Spiegel BMR, Harris L, Lucak S, Mayer E, Naliboff B, Bolus R, Esrailian E, Chey WD, Lembo A, Karsan H, Tillisch K, Dulai G, Talley J, Chang L 
Publication American Journal of Gastroenterology. 2009 [Epub ahead of print] 
Article PDF Not Available
Title Bacterial overgrowth and irritable bowel syndrome: unifying hypothesis or a spurious consequence of proton pump inhibitors? 
Author(s) Spiegel BM, Chey WD, Chang L. 
Publication American Journal of Gastroenterology. 2008 103(12):2972-6. 
Article View/Download Article
Title Predictors of patient-assessed illness severity in irritable bowel syndrome.  
Author(s) Spiegel BMR, Strickland A, Naliboff B, Mayer E, Chang L 
Publication American Journal of Gastroenterology. 2008 (Jun 30 – Epub ahead of print) 
Article View/Download Article
Title Functional GI disorders: From animal models to drug development. 
Author(s) Mayer EA, Bradesi S, Chang L, Spiegel BMR, Bueller JA, Naliboff BD 
Publication Gut 2007 
Article View/Download Article
Title Characterization of the alternating bowel habit subtype in patients with irritable bowel syndrome. 
Author(s) Tillisch K, Labus JS, Naliboff BD, Bolus R, Shetzline M, Mayer EA, Chang L. 
Publication Am J Gastroenterol. 2005;100:896-904 
Article View/Download Article
Title Differences in brain responses to visceral pain between patients with irritable bowel syndrome and ulcerative colitis. 
Author(s) Mayer EA, Berman S, Suyenobu B, Labus J, Mandelkern MA, Naliboff BD, Chang L. 
Publication Pain. 2005 Jun;115(3):398-409 
Article PDF Not Available
Title Impact of irritable bowel syndrome on patients' lives: development and psychometric documentation of a disease-specific measure for use in clini 
Author(s) Longstreth GF, Bolus R, Naliboff B, Chang L, Kulich KR, Carlsson J, Mayer EA, Naesdal J, Wiklund IK. 
Publication Eur J Gastroenterol Hepatol. 2005;17:411-20 
Article View/Download Article
Title Is a negative colonoscopy associated with improved health-related quality of life or reassurance in irritable bowel syndrome? 
Author(s) Spiegel BMR, Gralnek IM, Bolus R, Mayer E, Chang L, Dulai GS, Naliboff B. 
Publication Gastrointestinal Endoscopy 2005;62:892-899 
Article View/Download Article
Title Traditional Chinese medicine based subgrouping of irritable bowel syndrome patients. 
Author(s) Tan S, Tillisch K, Bolus R, Olivas T, Naliboff L, Chang L, Spiegel BMR, Mayer EA S. 
Publication Am J Chin Med. 2005;33(3):365-79 
Article View/Download Article
Title Clinical determinants of health-related quality of life in patients with irritable bowel syndrome. 
Author(s) Spiegel BMR, Gralnek IM, Mayer EB, Bolus R, Dulai GS, Chang L, Naliboff B. 
Publication Archives of Internal Medicine 2004;164:1773-1780 
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Title Racial differences in the impact of irritable bowel syndrome on health-related quality of life. 
Author(s) Gralnek IM, Hays RD, Kilbourne AM, Chang L, Mayer EA. 
Publication Journal of Clinical Gastroenterology. 2004;38:782-9 
Article View/Download Article
Title The effect of life stress on symptoms of heartburn. 
Author(s) Naliboff BD, Mayer M, Fass R, Fitzgerald LZ, Chang L, Bolus R, Mayer EA. 
Publication Psychosom Med. 2004;66:426-34 
Article PDF Not Available
Title The effect of life stress on symptoms of heartburn. 
Author(s) Naliboff BD, Mayer M, Fass R, Fitzgerald LZ, Chang L, Bolus R, Mayer EA. 
Publication Psychosom Med. 2004 May-Jun;66(3):426-34. 
Article PDF Not Available
Title The Visceral Sensitivity Index: development and validation of a gastrointestinal symptom-specific anxiety scale. 
Author(s) Labus JS, Bolus R, Chang L, Wiklund I, Naesdal J, Mayer EA, Naliboff BD. 
Publication Aliment Pharmacol Ther. 2004;20:89-97 
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Title Prevalence of irritable bowel syndrome among university students: the roles of worry, neuroticism, anxiety sensitivity and visceral anxiety. 
Author(s) Hazlett-Stevens H, Craske MG, Mayer EA, Chang L, Naliboff BD. 
Publication J Psychosom Res. 2003 Dec;55(6):501-5. 
Article PDF Not Available
Title Evolving pathophysiological model of functional gastrointestinal disorders: implications for treatment 
Author(s) Mayer EA, Naliboff BD, Chang L. 
Publication Eur J Surg Suppl. 2002;(587):3-9 
Article PDF Not Available
Title Hospital care for low-risk patients with acute, nonvariceal upper GI hemorrhage: a comparison of neighboring community and tertiary care centers. 
Author(s) Oei TT, Dulai GS, Gralnek IM, Chang D, Kilbourne AM, Sale GA. 
Publication Am J Gastroenterol. 2002;97:2271-8 
Article View/Download Article
Title Is there a difference between abdominal pain and discomfort in moderate to severe IBS patients? 
Author(s) Sach J, Bolus R, Fitzgerald L, Naliboff BD, Chang L, Mayer EA. 
Publication Am J Gastroenterol. 2002;97:3131-8 
Article PDF Not Available
Title Over-utilization of healthcare resources for low-risk patients with acute, non-variceal upper gastrointestinal hemorrhage: a historical cohort study. 
Author(s) Dulai GS, Gralnek IM, Oei TT, Chang D, Alofaituli G, Gornbein J, Kahn K. 
Publication Gastrointestinal Endoscopy 2002;55:321-7 
Article PDF Not Available
Title Utilization of health care resources for low-risk patients with acute, nonvariceal upper GI hemorrhage: an historical cohort study. 
Author(s) Dulai GS, Gralnek IM, Oei TT, Chang D, Alofaituli G, Gornbein J, Kahn K. 
Publication Gastrointest Endosc. 2002;55:321-7 
Article PDF Not Available
Title Sensation of bloating and visible abdominal distension in patients with irritable bowel syndrome. 
Author(s) Chang L, Lee OY, Naliboff B, Schmulson M, Mayer EA. 
Publication Am J Gastroenterol. 2001 Dec;96(12):3341-7 
Article PDF Not Available
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